In order to study physical response of cloud seeding, the precipitation enhancement experiment of stratiform and embedded convective cloud on 8 July 2003 in Jilin Province was analyzed in this paper. The background area and response area of cloud seeding for artificial precipitation enhancement effect were identified, and the seedability of cloud was studied. The differences of cloud microphysical characteristics between background area and response area was analyzed. The results are as follows: (1) The ice crystal number concentration in response area was significantly higher than that in the background area. In response area ice crystal number concentration with a diameter from 37.5 μm to 187.5 μm increased obviously. (2) The number concentration of small cloud particles with a diameter less than or equal to 18.5 μm in response area was lower than that in the background area, but the number concentration of large cloud particles with a diameter from 18.5 μm to 45.5 μm in response area was higher than that in the background area. (3) After cloud seeding, supercooled water content decreased, the radar echo intensity increased, and strong radar echo zone also increased. The physical response of cloud seeding was obvious in this experiment.